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Fetal and Neonatal Exposure to the Endocrine Disruptor Methoxychlor Causes Epigenetic Alterations in Adult Ovarian Genes

Exposure to endocrine-disrupting chemicals during development could alter the epigenetic programming of the genome and result in adult-onset disease. Methoxychlor (MXC) and its metabolites possess estrogenic, antiestrogenic, and antiandrogenic activities. Previous studies showed that fetal/neonatal...

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Bibliografiske detaljer
Main Authors: Zama, Aparna Mahakali, Uzumcu, Mehmet
Format: Artigo
Sprog:Inglês
Udgivet: The Endocrine Society 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754680/
https://ncbi.nlm.nih.gov/pubmed/19589859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2009-0499
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