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Targeted Genome-Wide Methylation and Gene Expression Analyses Reveal Signaling Pathways Involved in Ovarian Dysfunction after Developmental EDC Exposure in Rats

Transient exposure to methoxychlor (MXC), an environmental endocrine-disrupting chemical, during fetal and neonatal stages causes ovarian dysfunction in pubertal, adult, and aging animals. Adult animals have reduced number of ovulations and abnormal follicular composition associated with altered gen...

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Detalhes bibliográficos
Main Authors: Zama, Aparna Mahakali, Uzumcu, Mehmet
Formato: Artigo
Idioma:Inglês
Publicado em: Society for the Study of Reproduction, Inc. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589238/
https://ncbi.nlm.nih.gov/pubmed/23303685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.112.104802
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