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Inhibition of pre-mRNA splicing by synthetic branched nucleic acids

The cellular transformation of a precursor mRNA (pre-mRNA) into its mature or functional form proceeds by way of a splicing reaction, in which the exons are ligated to form the mature linear RNA and the introns are excised as branched or lariat RNAs. We have prepared a series of branched compounds (...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Carriero, Sandra, Damha, Masad J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2003
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC275466/
https://ncbi.nlm.nih.gov/pubmed/14576302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg824
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