Inhibition of pre-mRNA splicing by synthetic branched nucleic acids
The cellular transformation of a precursor mRNA (pre-mRNA) into its mature or functional form proceeds by way of a splicing reaction, in which the exons are ligated to form the mature linear RNA and the introns are excised as branched or lariat RNAs. We have prepared a series of branched compounds (...
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| Pubblicato in: | Nucleic Acids Res |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2003
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC275466/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14576302/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg824 |
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