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U2AF modulates poly(A) length control by the poly(A)-limiting element

The poly(A)-limiting element (PLE) restricts the length of the poly(A) tail to <20 nt when present in the terminal exon of a pre-mRNA. We previously identified a 65 kDa protein that could be cross-linked to a functional PLE, but not to an inactive mutant element. This binding was competed by poly...

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Bibliografske podrobnosti
Main Authors: Gu, Haidong, Schoenberg, Daniel R.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2003
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC275465/
https://ncbi.nlm.nih.gov/pubmed/14576315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg823
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