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Fast optimization of statistical potentials for structurally constrained phylogenetic models

BACKGROUND: Statistical approaches for protein design are relevant in the field of molecular evolutionary studies. In recent years, new, so-called structurally constrained (SC) models of protein-coding sequence evolution have been proposed, which use statistical potentials to assess sequence-structu...

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Detalhes bibliográficos
Main Authors: Bonnard, Cécile, Kleinman, Claudia L, Rodrigue, Nicolas, Lartillot, Nicolas
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754480/
https://ncbi.nlm.nih.gov/pubmed/19740424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-9-227
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