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A maximum likelihood framework for protein design

BACKGROUND: The aim of protein design is to predict amino-acid sequences compatible with a given target structure. Traditionally envisioned as a purely thermodynamic question, this problem can also be understood in a wider context, where additional constraints are captured by learning the sequence p...

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Detalhes bibliográficos
Main Authors: Kleinman, Claudia L, Rodrigue, Nicolas, Bonnard, Cécile, Philippe, Hervé, Lartillot, Nicolas
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1570151/
https://ncbi.nlm.nih.gov/pubmed/16808841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-7-326
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