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Precision of maximum likelihood estimation in adaptive designs
There has been increasing interest in trials that allow for design adaptations like sample size reassessment or treatment selection at an interim analysis. Ignoring the adaptive and multiplicity issues in such designs leads to an inflation of the type 1 error rate, and treatment effect estimates bas...
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| Publicado no: | Stat Med |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4755201/ https://ncbi.nlm.nih.gov/pubmed/26459506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.6761 |
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