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Eme1 is involved in DNA damage processing and maintenance of genomic stability in mammalian cells

Yeast and human Eme1 protein, in complex with Mus81, constitute an endonuclease that cleaves branched DNA structures, especially those arising during stalled DNA replication. We identified mouse Eme1, and show that it interacts with Mus81 to form a complex that preferentially cleaves 3′-flap structu...

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Publicado no:EMBO J
Principais autores: Abraham, Jacinth, Lemmers, Bénédicte, Hande, M.Prakash, Moynahan, Mary Ellen, Chahwan, Charly, Ciccia, Alberto, Essers, Jeroen, Hanada, Katsuhiro, Chahwan, Richard, Khaw, Aik Kia, McPherson, Peter, Shehabeldin, Amro, Laister, Rob, Arrowsmith, Cheryl, Kanaar, Roland, West, Stephen C., Jasin, Maria, Hakem, Razqallah
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2003
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Articles
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC275438/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14609959/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg580
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