Absolute Metabolite Concentrations and Implied Enzyme Active Site Occupancy in Escherichia coli

Absolute metabolite concentrations are critical to a quantitative understanding of cellular metabolism, as concentrations impact both the free energies and rates of metabolic reactions. Here we use liquid chromatography-tandem mass spectrometry to quantify more than 100 metabolite concentrations in...

Full description

Saved in:
Bibliographic Details
Main Authors: Bennett, Bryson D, Kimball, Elizabeth H, Gao, Melissa, Osterhout, Robin, Van Dien, Stephen J, Rabinowitz, Joshua D
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754216/
https://ncbi.nlm.nih.gov/pubmed/19561621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.186
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items