SPHINGOSINE-1-PHOSPHATE RECEPTORS MEDIATE NEUROMODULATORY FUNCTIONS IN THE CNS

Sphingosine-1-phosphate is a ubiquitous, lipophilic cellular mediator that acts in part by activation of G-protein-coupled receptors. Modulation of S1P signaling is an emerging pharmacotherapeutic target for immunomodulatory drugs. Although multiple S1P receptor types exist in the CNS, little is kno...

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Autori principali: Sim-Selley, Laura J., Goforth, Paulette B., Mba, Mba U., Macdonald, Timothy L., Lynch, Kevin R., Milstien, Sheldon, Spiegel, Sarah, Satin, Leslie S., Welch, Sandra P., Selley, Dana E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754148/
https://ncbi.nlm.nih.gov/pubmed/19493165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2009.06202.x
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