Assessment of rituximab’s immunomodulatory synovial effects (ARISE trial). 1: clinical and synovial biomarker results

OBJECTIVE: Treatment with the anti-CD20 monoclonal antibody (mAb) rituximab is effective in rheumatoid arthritis (RA). Marked depletion of circulating B cells, seen in almost all patients, does not correlate with efficacy. The potential synovial immunomodulatory effects of rituximab have not been fu...

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Main Authors: Kavanaugh, A, Rosengren, S, Lee, S J, Hammaker, D, Firestein, G S, Kalunian, K, Wei, N, Boyle, D L
Format: Artigo
Jezik:Inglês
Izdano: 2007
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754142/
https://ncbi.nlm.nih.gov/pubmed/17644541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2007.074229
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