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Synovial tissue response to rituximab: mechanism of action and identification of biomarkers of response

OBJECTIVE: To investigate the synovial tissue in patients with rheumatoid arthritis (RA) treated with rituximab and to identify possible predictors of clinical response. METHODS: A total of 24 patients with RA underwent synovial biopsy before, 4 and 16 weeks after initiation of rituximab treatment (...

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Main Authors: Thurlings, R M, Vos, K, Wijbrandts, C A, Zwinderman, A H, Gerlag, D M, Tak, P P
Format: Artigo
Jezik:Inglês
Izdano: BMJ Publishing Group 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2564787/
https://ncbi.nlm.nih.gov/pubmed/17965121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2007.080960
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