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From Synovial Tissue to Peripheral Blood: Myeloid Related Protein 8/14 Is a Sensitive Biomarker for Effective Treatment in Early Drug Development in Patients with Rheumatoid Arthritis

OBJECTIVE: The change in number of CD68-positive sublining macrophages in serial synovial biopsies has been successfully used to discriminate on the group level between effective and ineffective treatment during early drug development in rheumatoid arthritis (RA) patients. Measurement of a soluble b...

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Detalhes bibliográficos
Main Authors: Choi, Ivy Y., Gerlag, Danielle M., Holzinger, Dirk, Roth, Johannes, Tak, Paul P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148438/
https://ncbi.nlm.nih.gov/pubmed/25166859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0106253
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