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C/EBPβ: a major PML–RARA-responsive gene in retinoic acid-induced differentiation of APL cells

In acute promyelocytic leukemia (APL), the translocation t(15;17) induces a block at the promyelocytic stage of differentiation in an all-trans-retinoic acid (ATRA)-responsive manner. Here we report that upon treatment with ATRA, t(15;17) cells (NB4) reveal a very rapid increase in protein level and...

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Détails bibliographiques
Auteurs principaux: Duprez, Estelle, Wagner, Katharina, Koch, Heike, Tenen, Daniel G.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC275413/
https://ncbi.nlm.nih.gov/pubmed/14592978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg556
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