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Role of hydroxycarbamide in prevention of complications in patients with sickle cell disease

Sickle cell disease (SCD) is a genetically inherited condition caused by a point mutation in the beta globin gene. This results in the production of the abnormal hemoglobin, sickle hemoglobin (HbS). Hydroxycarbamide, is an antimetabolite/cytotoxic which works by inhibiting ribonucleotide reductase,...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Wiles, NM, Howard, J
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Dove Medical Press 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754089/
https://ncbi.nlm.nih.gov/pubmed/19816573
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