Alternative interactions between the Tn7 transposase and the Tn7 target DNA binding protein regulate target immunity and transposition
The Tn7 transposon avoids inserting into a target DNA that contains a pre-existing copy of Tn7. This phenomenon, known as ‘target immunity’, is established when TnsB, a Tn7 transposase subunit, binds to Tn7 sequences in the target DNA and mediates displacement of TnsC, a critical transposase activat...
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| Опубликовано в:: | EMBO J |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2003
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC275408/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14592987/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg551 |
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