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Alternative interactions between the Tn7 transposase and the Tn7 target DNA binding protein regulate target immunity and transposition

The Tn7 transposon avoids inserting into a target DNA that contains a pre-existing copy of Tn7. This phenomenon, known as ‘target immunity’, is established when TnsB, a Tn7 transposase subunit, binds to Tn7 sequences in the target DNA and mediates displacement of TnsC, a critical transposase activat...

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Bibliografiske detaljer
Udgivet i:EMBO J
Principais autores: Skelding, Zachary, Queen-Baker, Jennie, Craig, Nancy L.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2003
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC275408/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14592987/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg551
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