Bacterial lipopeptide triggers massive albuminuria in murine lupus nephritis by activating Toll-like receptor 2 at the glomerular filtration barrier

What are the molecular mechanisms of bacterial infections triggering or modulating lupus nephritis? In nephritic MRL(lpr/lpr) mice, transient exposure to bacterial cell wall components such as lipopeptide or lipopolysaccharide (LPS) increased splenomegaly, the production of DNA autoantibodies, and s...

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Autors principals: Pawar, Rahul D, Castrezana-Lopez, Liliana, Allam, Ramanjaneyulu, Kulkarni, Onkar P, Segerer, Stephan, Radomska, Ewa, Meyer, Tobias N, Schwesinger, Catherine-Meyer, Akis, Nese, Gröne, Hermann-Josef, Anders, Hans-Joachim
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2009
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753940/
https://ncbi.nlm.nih.gov/pubmed/19175801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2008.02948.x
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