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Cytotoxic T-lymphocyte antigen 4 blockade augments the T-cell response primed by attenuated Listeria monocytogenes resulting in more rapid clearance of virulent bacterial challenge

Cytotoxic T-lymphocyte antigen 4 (CTLA-4) uniformly suppresses antigen-specific T cells during chronic infection with bacterial, parasitic or viral pathogens. However, the importance of CTLA-4 in controlling the T-cell response during acute infection or after priming with live attenuated vaccine vec...

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Detalles Bibliográficos
Main Authors: Rowe, Jared H, Johanns, Tanner M, Ertelt, James M, Lai, Joseph C, Way, Sing Sing
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753913/
https://ncbi.nlm.nih.gov/pubmed/19191906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2008.03001.x
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