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Peripheral blood CD27(+) IgG(+) B cells rapidly proliferate and differentiate into immunoglobulin-secreting cells after exposure to low CD154 interaction

In vitro CD40 stimulation of human B cells isolated from lymphoid organs is dominated by memory B cells undergoing faster proliferation and higher differentiation than naive B cells. In contrast, we previously reported that blood memory B cells mainly differentiate into immunoglobulin-secreting cell...

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Библиографические подробности
Главные авторы: Fecteau, Jessie F, Roy, Annie, Néron, Sonia
Формат: Artigo
Язык:Inglês
Опубликовано: Blackwell Science Inc 2009
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753896/
https://ncbi.nlm.nih.gov/pubmed/19016905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2008.02976.x
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