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Candidate Vaccine Sequences to Represent Intra- and Inter-Clade HIV-1 Variation
A likely key factor in the failure of a HIV-1 vaccine based on cytotoxic T lymphocytes (CTL) is the natural immunodominance of epitopes that fall in variable regions of the proteome, which both increases the chance of epitope sequence mismatch with the incoming challenge strain and replicates the pa...
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2009
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2753653/ https://ncbi.nlm.nih.gov/pubmed/19812689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007388 |
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