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Involvement of insulin-degrading enzyme in the clearance of beta-amyloid at the blood-CSF barrier: Consequences of lead exposure

BACKGROUND: Alzheimer's disease (AD) is characterized by the deposition of beta-amyloid (Aβ) peptides in the brain extracellular matrix, resulting in pathological changes and neurobehavioral deficits. Previous work from this laboratory demonstrated that the choroid plexus (CP) possesses the cap...

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Sonraí Bibleagrafaíochta
Main Authors: Behl, Mamta, Zhang, Yanshu, Zheng, Wei
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753621/
https://ncbi.nlm.nih.gov/pubmed/19747378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-8454-6-11
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