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Modeling time variant distributions of cellular lifespans: increases in circulating reticulocyte lifespans following double phlebotomies in sheep

Many pharmacodynamic (PD) models of cellular response assume a single and time invariant lifespan of all cells, despite the existence of a true underlying distribution of cellular lifespans and known changes in the lifespan distributions with time. To account for these features of cellular populatio...

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Detalhes bibliográficos
Main Authors: Freise, Kevin J., Widness, John A., Schmidt, Robert L., Veng-Pedersen, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753503/
https://ncbi.nlm.nih.gov/pubmed/18553126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10928-008-9089-1
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