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Fluorescence Correlation Spectroscopy of Phosphatidylinositol-specific Phospholipase C Monitors the Interplay of Substrate and Activator Lipid Binding
Phosphatidylinositol-specific phospholipase C (PI-PLC) enzymes simultaneously interact with the substrate, PI, and with non-substrate lipids such as phosphatidylcholine (PC). For Bacillus thuringiensis PI-PLC these interactions are synergistic with maximal catalytic activity observed at low to moder...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2753481/ https://ncbi.nlm.nih.gov/pubmed/19548649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900633p |
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