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The Sequence Specificity of Homeodomain-DNA Interaction

The Drosophila developmental gene, engrailed, encodes a sequence-specific DNA binding activity. Using deletion constructs expressed as fusion proteins in E. coli, we localized this activity to the conserved homeodomain (HD). The binding site consensus, TCAATTAAAT, is found in clusters in the engrail...

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Bibliografische gegevens
Hoofdauteurs: Desplan, Claude, Theis, Jim, O’Farrell, Patrick H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1988
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753412/
https://ncbi.nlm.nih.gov/pubmed/3046753
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