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Augmenting DAF levels in vivo ameliorates experimental autoimmune encephalomyelitis
Recent studies in experimental autoimmune encephalomyelitis (EAE) have found that CNS injury in Daf1(-/-) mice is much greater than in wild types (WTs), suggesting that upregulating DAF levels in vivo might ameliorate disease. To test this, we generated a Daf1 transgenic (Tg) mouse which had elevate...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2753188/ https://ncbi.nlm.nih.gov/pubmed/19660813 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2009.07.003 |
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