Host Genetic Variation Affects Resistance to Infection with a Highly Pathogenic H5N1 Influenza A Virus in Mice

Despite the prevalence of H5N1 influenza viruses in global avian populations, comparatively few cases have been diagnosed in humans. Although viral factors almost certainly play a role in limiting human infection and disease, host genetics most likely contribute substantially. To model host factors...

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Autores principales: Boon, Adrianus C. M., deBeauchamp, Jennifer, Hollmann, Anna, Luke, Jennifer, Kotb, Malak, Rowe, Sarah, Finkelstein, David, Neale, Geoffrey, Lu, Lu, Williams, Robert W., Webby, Richard J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2009
Materias:
Pathogenesis and Immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753106/
https://ncbi.nlm.nih.gov/pubmed/19706712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00514-09
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