Identification of Francisella tularensis Live Vaccine Strain CuZn Superoxide Dismutase as Critical for Resistance to Extracellularly Generated Reactive Oxygen Species

Francisella tularensis is an intracellular pathogen whose survival is in part dependent on its ability to resist the microbicidal activity of host-generated reactive oxygen species (ROS) and reactive nitrogen species (RNS). In numerous bacterial pathogens, CuZn-containing superoxide dismutases (SodC...

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Autori principali: Melillo, Amanda A., Mahawar, Manish, Sellati, Timothy J., Malik, Meenakshi, Metzger, Dennis W., Melendez, J. Andres, Bakshi, Chandra Shekhar
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2009
Soggetti:
Molecular Biology of Pathogens
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753026/
https://ncbi.nlm.nih.gov/pubmed/19684141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00534-09
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