Identification of Francisella tularensis Live Vaccine Strain CuZn Superoxide Dismutase as Critical for Resistance to Extracellularly Generated Reactive Oxygen Species

Francisella tularensis is an intracellular pathogen whose survival is in part dependent on its ability to resist the microbicidal activity of host-generated reactive oxygen species (ROS) and reactive nitrogen species (RNS). In numerous bacterial pathogens, CuZn-containing superoxide dismutases (SodC...

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Detalhes bibliográficos
Main Authors: Melillo, Amanda A., Mahawar, Manish, Sellati, Timothy J., Malik, Meenakshi, Metzger, Dennis W., Melendez, J. Andres, Bakshi, Chandra Shekhar
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Molecular Biology of Pathogens
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753026/
https://ncbi.nlm.nih.gov/pubmed/19684141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00534-09
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