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Therapeutic Targeting of ATP7B in Ovarian Carcinoma

PURPOSE: Resistance to platinum chemotherapy remains a significant problem in ovarian carcinoma. Here, we examined the biological mechanisms and therapeutic potential of targeting a critical platinum resistance gene, ATP7B, using both in vitro and in vivo models. EXPERIMENTAL DESIGN: Expression of A...

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Bibliographische Detailangaben
Hauptverfasser: Mangala, Lingegowda S., Zuzel, Vesna, Schmandt, Rosemarie, Leshane, Erik S., Halder, Jyotsna B., Armaiz-Pena, Guillermo N., Spannuth, Whitney A., Tanaka, Takemi, Shahzad, Mian M.K., Lin, Yvonne G., Nick, Alpa M., Danes, Christopher G., Lee, Jeong-Won, Jennings, Nicholas B., Vivas-Mejia, Pablo E., Wolf, Judith K., Coleman, Robert L., Siddik, Zahid H., Lopez-Berestein, Gabriel, Lutsenko, Svetlana, Sood, Anil K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752981/
https://ncbi.nlm.nih.gov/pubmed/19470734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-2306
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