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The Development of Resistance to Passive Therapy by a Potently Neutralizing Humanized West Nile Virus Monoclonal Antibody
Previous studies have established the therapeutic efficacy of humanized E16 (hE16) monoclonal antibody against West Nile virus (WNV) in animals. Here, we assess the potential for WNV strains encoding mutations in the hE16 epitope to resist passive immunotherapy and for the selection of neutralizatio...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2752978/ https://ncbi.nlm.nih.gov/pubmed/19527169 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/599794 |
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