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Synthesis of (+)-CP-99,994 via Pd(0)-Catalyzed Asymmetric Allylic and Homoallylic C-H Diamination of Terminal Olefin

[Image: see text] This paper describes an asymmetric synthesis of the potent substance P receptor antagonist (+)-CP-99,994 from 4-phenyl-1-butene via Pd(0)-catalyzed asymmetric allylic and homoallylic C-H diamination.

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Autori principali: Fu, Renzhong, Zhao, Baoguo, Shi, Yian
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752905/
https://ncbi.nlm.nih.gov/pubmed/19778085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo9015584
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