Association of the proprotein convertase subtilisin/kexin-type 2 (PCSK2) gene with type 2 diabetes in an African American population

In a genome-wide scan for type 2 diabetes (T2DM) in African American (AA) families, ordered subsets analysis (OSA) provided evidence for linkage to chromosome 20p in a subset with later age at diagnosis (max. LOD 2.57, P = 0.008). The proprotein convertase subtilisin/kexin-type 2 (PCSK2) gene is wit...

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Main Authors: Leak, Tennille S., Keene, Keith L., Langefeld, Carl D., Gallagher, Carla J., Mychaleckyj, Josyf C., Freedman, Barry I., Bowden, Donald W., Rich, Stephen S., Sale, Michèle M.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752824/
https://ncbi.nlm.nih.gov/pubmed/17618154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2007.05.014
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