Catechol-O-Methyltransferase Expression and 2-Methoxyestradiol Affect Microtubule Dynamics and Modify Steroid Receptor Signaling in Leiomyoma Cells

CONTEXT: Development of optimal medicinal treatments of uterine leiomyomas represents a significant challenge. 2-Methoxyestradiol (2ME) is an endogenous estrogen metabolite formed by sequential action of CYP450s and catechol-O-methyltransferase (COMT). Our previous study demonstrated that 2ME is a p...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Salama, Salama A., Kamel, Marwa W., Botting, Shaleen, Salih, Sana M., Borahay, Mostafa A., Hamed, Ahmed A., Kilic, Gokhan S., Saeed, Muhammad, Williams, Marian Y., Diaz-Arrastia, Concepcion R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752809/
https://ncbi.nlm.nih.gov/pubmed/19809499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007356
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados