Heparin-binding EGF-like Growth Factor Signaling in Flow-induced Arterial Remodeling

Heparin-binding EGF-like growth factor (HB-EGF) is activated by reduced endothelial shear stress and stimulates smooth muscle cell (SMC) proliferation in vitro. More- over, HB-EGF is augmented at sites of intimal hyperplasia and atherosclerosis— conditions favored by low/disturbed shear stress. We t...

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Bibliographic Details
Main Authors:	Zhang, Hua, Sunnarborg, Susan W, McNaughton, K Kirk, Johns, Terrance G, Lee, David C, Faber, James E
Format:	Artigo
Language:	Inglês
Published:	2008
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2752633/ https://ncbi.nlm.nih.gov/pubmed/18436796 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.108.171728
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Heparin-binding EGF-like Growth Factor Signaling in Flow-induced Arterial Remodeling

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