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Orbital fibroblasts from patients with thyroid-associated ophthalmopathy over-express CD40: CD154 hyper-induces IL-6, IL-8 and MCP-1

PURPOSE: Fibroblast diversity represents an emerging concept critical to our understanding of tissue inflammation, repair and remodeling. Orbital fibroblasts heterogeneously display Thy-1 and exhibit unique phenotypic attributes that may explain the susceptibility of the human orbit to thyroid-assoc...

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Detalhes bibliográficos
Main Authors: Hwang, Catherine, Afifiyan, Nikoo, Sand, Daniel, Naik, Vibha, Said, Jonathan, Pollock, Stephen, Chen, Beiling, Phipps, Richard P., Goldberg, Robert A, Smith, Terry J., Douglas, Raymond S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752347/
https://ncbi.nlm.nih.gov/pubmed/19117935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.08-2328
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