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Human Regulatory T cells and Autoimmunity

CD4(+)CD25(+) regulatory T cells (Tregs) appear to be critical in regulating immune responses to self-antigens. Treg deficiency is associated with several human autoimmune diseases. Although substantial progress has been made in the study of murine and human Tregs, their fundamental mechanism of act...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Costantino, Cristina Maria, Baecher-Allan, Clare M., Hafler, David A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752283/
https://ncbi.nlm.nih.gov/pubmed/18395861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200738104
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