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Mechanical constraints on Hin subunit rotation imposed by the Fis-enhancer system and DNA supercoiling during site-specific recombination

Hin, a member of the serine family of site-specific recombinases, regulates gene expression by inverting a DNA segment. DNA inversion requires assembly of an invertasome complex in which a recombinational enhancer DNA segment bound by the Fis protein associates with the Hin synaptic complex at the b...

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Bibliografiske detaljer
Main Authors: Dhar, Gautam, Heiss, John K., Johnson, Reid C.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752211/
https://ncbi.nlm.nih.gov/pubmed/19560425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.05.020
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