The peptidyl-prolyl isomerase Pin1 determines parathyroid hormone mRNA levels and stability in rat models of secondary hyperparathyroidism

Secondary hyperparathyroidism is a major complication of chronic kidney disease (CKD). In experimental models of secondary hyperparathyroidism induced by hypocalcemia or CKD, parathyroid hormone (PTH) mRNA levels increase due to increased PTH mRNA stability. K-homology splicing regulator protein (KS...

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Bibliographic Details
Main Authors: Nechama, Morris, Uchida, Takafumi, Mor Yosef-Levi, Irit, Silver, Justin, Naveh-Many, Tally
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2009
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752082/
https://ncbi.nlm.nih.gov/pubmed/19770516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI39522
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