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Negative feedback maintenance of heme homeostasis by its receptor, Rev-erbα
Intracellular heme levels must be tightly regulated to maintain proper mitochondrial respiration while minimizing toxicity, but the homeostatic mechanisms are not well understood. Here we report a novel negative feedback mechanism whereby the nuclear heme receptor Rev-erbα tightly controls the level...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2751986/ https://ncbi.nlm.nih.gov/pubmed/19710360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1825809 |
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