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Mixing and Matching Detergents for Membrane Protein NMR Structure Determination

One major obstacle to membrane protein structure determination is the selection of a detergent micelle that mimics the native lipid bilayer. Currently, detergents are selected by exhaustive screening because the effects of protein-detergent interactions on protein structure are poorly understood. In...

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Bibliografiske detaljer
Main Authors: Columbus, Linda, Lipfert, Jan, Jambunathan, Kalyani, Fox, Daniel A., Sim, Adelene Y. L., Doniach, Sebastian, Lesley, Scott A.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2751809/
https://ncbi.nlm.nih.gov/pubmed/19425578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja808776j
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