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Dissecting electrostatic screening, specific ion binding, and ligand binding in an energetic model for glycine riboswitch folding

Riboswitches are gene-regulating RNAs that are usually found in the 5′-untranslated regions of messenger RNA. As the sugar-phosphate backbone of RNA is highly negatively charged, the folding and ligand-binding interactions of riboswitches are strongly dependent on the presence of cations. Using smal...

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Bibliografski detalji
Glavni autori: Lipfert, Jan, Sim, Adelene Y.L., Herschlag, Daniel, Doniach, Sebastian
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844619/
https://ncbi.nlm.nih.gov/pubmed/20194520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1985110
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