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Dissecting electrostatic screening, specific ion binding, and ligand binding in an energetic model for glycine riboswitch folding
Riboswitches are gene-regulating RNAs that are usually found in the 5′-untranslated regions of messenger RNA. As the sugar-phosphate backbone of RNA is highly negatively charged, the folding and ligand-binding interactions of riboswitches are strongly dependent on the presence of cations. Using smal...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Cold Spring Harbor Laboratory Press
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2844619/ https://ncbi.nlm.nih.gov/pubmed/20194520 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1985110 |
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