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Sequence features associated with microRNA strand selection in humans and flies

BACKGROUND: During microRNA (miRNA) maturation in humans and flies, Drosha and Dicer cut the precursor transcript, thereby producing a short RNA duplex. One strand of this duplex becomes a functional component of the RNA-Induced Silencing Complex (RISC), while the other is eliminated. While thermody...

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Библиографические подробности
Главные авторы: Hu, Hai Yang, Yan, Zheng, Xu, Ying, Hu, Hao, Menzel, Corinna, Zhou, Yan Hong, Chen, Wei, Khaitovich, Philipp
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2009
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2751786/
https://ncbi.nlm.nih.gov/pubmed/19732433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-10-413
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