Sequence features associated with microRNA strand selection in humans and flies

BACKGROUND: During microRNA (miRNA) maturation in humans and flies, Drosha and Dicer cut the precursor transcript, thereby producing a short RNA duplex. One strand of this duplex becomes a functional component of the RNA-Induced Silencing Complex (RISC), while the other is eliminated. While thermody...

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Hlavní autoři: Hu, Hai Yang, Yan, Zheng, Xu, Ying, Hu, Hao, Menzel, Corinna, Zhou, Yan Hong, Chen, Wei, Khaitovich, Philipp
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2009
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2751786/
https://ncbi.nlm.nih.gov/pubmed/19732433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-10-413
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