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Relative importance of complement-mediated bactericidal and opsonic activity for protection against meningococcal disease
Killing of Neisseria meningitidis can result from complement-mediated bactericidal activity (SBA) or opsonophagocytosis (OPA), or a combination of the two mechanisms. While SBA titers ≥1:4 confer protection, recent evidence suggests that this threshold titer may not be required. For example, the inc...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2751589/ https://ncbi.nlm.nih.gov/pubmed/19477054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2009.04.066 |
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