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Importance of Complement Source in Measuring Meningococcal Bactericidal Titers

Complement-mediated bactericidal antibodies in serum confer protection against meningococcal disease. The minimum protective titer is estimated to be between 1:4 and 1:8 when measured by the Goldschneider assay performed with human complement, the assay used in the 1960s to establish the correlation...

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Detalhes bibliográficos
Main Authors: Santos, George F., Deck, R. Randall, Donnelly, John, Blackwelder, William, Granoff, Dan M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC96111/
https://ncbi.nlm.nih.gov/pubmed/11329468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CDLI.8.3.616-623.2001
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