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The chinchilla microdialysis model for the study of antibiotic distribution to middle ear fluid

In cases of slow or limited penetration of an antibiotic to the site of infection such as in acute otitis media (the middle ear), plasma levels of the agent may not reflect the concentrations that are relevant in determining clinical outcome. There is a need for a model that allows prediction of the...

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Bibliografske podrobnosti
Main Authors: Cheung, Belinda W. Y., Liu, Wei, Ji, Ping, Cartier, Linda L., Li, Zhihong, Mostafa, Nael, Sawchuk, Ronald J.
Format: Artigo
Jezik:Inglês
Izdano: Springer-Verlag 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2751422/
https://ncbi.nlm.nih.gov/pubmed/16584132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/aapsj080105
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