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Estimating Amoxicillin Influx/Efflux in Chinchilla Middle Ear Fluid and Simultaneous Measurement of Antibacterial Effect

Understanding the transport process and the factors that control the influx/efflux of antibiotics between plasma and middle ear fluid is essential in optimizing the antimicrobial efficacy in the treatment of acute otitis media. In this study, an experimental chinchilla model with the application of...

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Detalhes bibliográficos
Main Authors: Huang, Yue, Yang, Zheng, Cartier, Linda, Cheung, Belinda, Sawchuk, Ronald J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2167983/
https://ncbi.nlm.nih.gov/pubmed/17923485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00405-07
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