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Monoamine oxidase inhibitory properties of some benzazoles: Structure-; Activity relationships

Benzazoles containing two or three nitrogen atoms were screened for their inhibitory activity toward monoamine oxidases MAO-A and MAO-B. In order to clarify the mechanism of interaction of these compounds with the enzyme, their electronic structure was calculated at the ab initio level and the influ...

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Bibliografiske detaljer
Main Authors: Grandi, Teresa, Sparatore, Fabio, Gnerre, Carmela, Crivori, Patrizia, Carrupt, Pierre-Alain, Testa, Bernard
Format: Artigo
Sprog:Inglês
Udgivet: Springer-Verlag 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2751346/
https://ncbi.nlm.nih.gov/pubmed/11741212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/ps010416
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