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Protein binding predictions in infants

Plasma binding protein levels are lower in the newborn than in the adult and gradually increase with age. At birth, human serum albumin (HSA) concentrations are close to adult levels (75%–80%), while alpha 1-acid glycoprotein (AAG) is initially half the adult concentration. As a result, the extent o...

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Detalhes bibliográficos
Main Authors: McNamara, Patrick J., Alcorn, Jane
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2751289/
https://ncbi.nlm.nih.gov/pubmed/12049488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/ps040104
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