Performance of a diffusional clearance model for beta-lactam antimicrobial agents as influenced by extravascular protein binding and interstitial fluid kinetics.

A physiological model based on diffusional clearance (CLD) of drug between plasma and interstitial fluid (IF) was used to describe the disposition of beta-lactam antimicrobial agents. The CLD represents the movement of drug in and out of physiological spaces and is dependent only on the transfer pro...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Fleishaker, J C, McNamara, P J
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1985
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC180255/
https://ncbi.nlm.nih.gov/pubmed/4073859
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