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Performance of a diffusional clearance model for beta-lactam antimicrobial agents as influenced by extravascular protein binding and interstitial fluid kinetics.

A physiological model based on diffusional clearance (CLD) of drug between plasma and interstitial fluid (IF) was used to describe the disposition of beta-lactam antimicrobial agents. The CLD represents the movement of drug in and out of physiological spaces and is dependent only on the transfer pro...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Fleishaker, J C, McNamara, P J
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1985
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC180255/
https://ncbi.nlm.nih.gov/pubmed/4073859
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